Ultrafiltration Equipment For Pharmaceutical Companies

The core of this Ultrafiltration Equipment for Pharmaceutical Companies is the ultrafiltration membrane, filled with nanoscale pores of uniform and controllable size. Target substances larger than the pores, such as proteins and viruses, are trapped by the membrane and remain in the container, becoming a concentrate; while small molecule impurities like water and salt pass through directly and are discharged. The entire process is carried out at room temperature, without heating or cooling, maximizing the preservation of the activity of biomolecules.

It's also flexible in operation. For large-scale production, tangential flow filtration is used, where the liquid flows at high speed along the membrane surface, flushing away trapped substances and preventing membrane clogging; for small batches of samples, dead-end filtration is used, where the liquid is directly flushed against the membrane.

Product Parameters

In pharmaceutical plants, Ultrafiltration Equipment for Pharmaceutical Companies serves three main purposes. First, concentration: thickening useful substances like vaccines and antibodies by removing excess water. Second, percolation: replacing the original buffer solution and removing small molecule impurities like salts and preservatives—a crucial step for ensuring drug purity. Third, fractionation: separating antibodies from unbound small molecule drugs for precise screening of desired components. For example, in vaccine production, the equipment can operate stably once set to a molecular weight cutoff of 100-300 kDa and a pressure of 0.5-1.5 bar.

This Ultrafiltration Equipment for Pharmaceutical Companies is designed entirely for pharmaceutical safety. Components in contact with the drug solution are made of safe materials such as 316L stainless steel and standard-compliant plastics. Connections are seamless, minimizing drug residue and facilitating cleaning. It also allows for online sterilization and cleaning; sterilization is achieved with 121°C steam, and cleaning with acid or alkaline detergents prevents cross-contamination between different batches of drugs. Moreover, the equipment has a compact internal pipeline design, which reduces drug residue and achieves a yield of over 98%, helping pharmaceutical companies reduce waste and increase profits.